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Artiom Alhazov, Ion Petre, Sergey Verlan:
A Sequence-Based Analysis of the Pointer Distribution of Ciliate Genes

Techreport
Year: 2008
Number: 902
Institution: TUCS
Keywords: Ciliates, pointers, sequence analysis, pointer distribution
Laboratory: Computational Biomodelling

Abstract

It has long been known that the lengths of some of the pointers in the micronuclear ciliate genes are too short to allow for the unambiguous recognition of their coding and noncoding blocks. Many of these pointers have multiple occurrences along the gene, allowing for a very high number of possible divisions into coding and noncoding blocks. We investigate in this paper the pointer distribution of all currently sequenced micronuclear ciliate genes with the goal of identifying what distinguishes the real gene structure among all possible coding/noncoding divisions. We find a surprisingly sharp criterium in the total AT percentage of the IESs of each such division: the real gene has, in most cases, the maximum such percentage among all possible combinations.


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